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    October 11, 2017 at 1:10 am

    NEW YORK (Reuters Well being) – Tranquilizers often known as benzodiazepines and
    sure older antidepressants are linked with a higher likelihood of getting erectile dysfunction (ED), in accordance
    with a brand new survey.

    “Positively it confirms the tricyclics (antidepressants)” are tied to ED,
    stated Dr. Richard Balon, a psychiatry professor at Wayne State College Faculty of

    Contrary to another research, nonetheless, the analysis didn’t discover any elevated danger of ED amongst males taking blood-strain medications.

    “I do not know what to make of this,” mentioned Balon,
    who was not a part of the examine.

    Certain well being circumstances, reminiscent of excessive blood strain and diabetes, are danger components for impotence.

    Previous analysis has instructed that medications themselves, particularly when a man is taking a number of completely different prescription medication,
    are tied to a better danger for erectile dysfunction (see Reuters Well being story of December eight, 2011 right

    To see how that relationship shakes out with particular person remedy varieties, a analysis crew led by Varant Kupelian at New England Analysis Institutes in Watertown, Massachusetts,
    surveyed 2,301 males about their prescription drug use and their sexual operate.

    Erectile dysfunction was outlined as scoring 17 or beneath on the 25-level
    scale of a self-evaluation of erection firmness,
    reliability and satisfaction.

    The researchers discovered that about one in 5 of the males surveyed had ED.

    Among 60 males who had taken a tricyclic antidepressant within the final month, practically half additionally certified as having ED.

    In distinction, one quarter of the males who had
    not taken a tricyclic had ED.

    Popular tricyclic antidepressants embody amitryptyline, and the model title medicine Anafranil,
    Tofranil and Vivactil.

    After making an allowance for danger components for ED, resembling age and
    coronary heart illness, the researchers decided that males on these medicine had
    a greater than three-fold larger danger of experiencing ED.

    Men taking benzodiazepines resembling Valium, Xanax, Klonopin and Ativan, usually
    used to deal with anxiety, have been additionally greater than two occasions as more likely to have ED.

    Similar to males on tricyclics, practically half of males who had taken a benzodiazepine within the final
    month had ED, in comparison with a couple of quarter of males who
    had not taken the drug.

    The examine cannot say whether or not the medication are
    inflicting the sexual disorder, the erectile dysfunction is contributing
    to the psychiatric situation, or if maybe the 2 issues share an underlying trigger.

    “We actually can not say something about causation right here and we do not know what are the pathways that is likely to be performing on erection perform or not,” Kupelian informed Reuters Well being.

    Men taking hypertension medicine didn’t have a better danger of ED, Kupelian’s group studies
    within the medical journal BJU Worldwide.

    “This was a little bit unexpected, as a result of we thought we might see one thing,” stated Kupelian.

    He mentioned his research made certain to account for the hypertension itself in addition to different well being
    components which may clarify why his group did not see extra circumstances of ED among the many males taking hypertension treatment.

    Men taking anti-inflammatory medication have been additionally no extra more
    likely to have ED than males who did not take them.

    Balon suggested warning in deciphering the outcomes, significantly with regard to benzodiazepines, as
    a result of there have been a comparatively small variety of males – ninety – who had used these medications.

    Kupelian agreed that extra analysis is required. “These are exploratory analyses,” he mentioned.

    Kupelian stated the outcomes should not for use
    for making remedy suggestions, and if males are involved about
    their medications they need to discuss to their medical doctors.

    SOURCE: BJU Worldwide, on-line Could 14, 2013.

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